Hypothalamic sensing of fatty acids

  title={Hypothalamic sensing of fatty acids},
  author={Tony K. T. Lam and Gary J Schwartz and Luciano Rossetti},
  journal={Nature Neuroscience},
Selective regions of the brain, including the hypothalamus, are capable of gathering information on the body's nutritional status in order to implement appropriate behavioral and metabolic responses to changes in fuel availability. This review focuses on direct metabolic signaling within the hypothalamus. There is growing evidence supporting the idea that fatty acid metabolism within discrete hypothalamic regions can function as a sensor for nutrient availability that can integrate multiple… CONTINUE READING
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