Hypothalamic-pituitary-gonadal axis in depressed premenopausal women: elevated blood testosterone concentrations compared to normal controls.

@article{Baischer1995HypothalamicpituitarygonadalAI,
  title={Hypothalamic-pituitary-gonadal axis in depressed premenopausal women: elevated blood testosterone concentrations compared to normal controls.},
  author={W Baischer and G. Koinig and Beda Hartmann and Johannes Huber and Gerhard Langer},
  journal={Psychoneuroendocrinology},
  year={1995},
  volume={20 5},
  pages={553-9}
}
To assess the function of the hypothalamic-pituitary-gonadal (HPG) axis in major depression, a multihormonal study was carried out in 20 depressed premenopausal women. Serum concentrations of LH, FSH, estradiol, progesterone, testosterone, and GnRH-stimulated LH and FSH were measured before initiation of treatment (on the first day after menstruation) and during clomipramine treatment (same time one menstrual cycle later). Significantly higher blood concentrations of testosterone were found in… CONTINUE READING