Hypothalamic-pituitary-adrenocortical function in mixed and pure mania.

  title={Hypothalamic-pituitary-adrenocortical function in mixed and pure mania.},
  author={Alan C. Swann and Peter E. Stokes and Robert F. Casper and Steven Secunda and Charles L. Bowden and Nancy Berman and Martin M. Katz and Eli Robins},
  journal={Acta psychiatrica Scandinavica},
  volume={85 4},
There is little information about hypothalamic-pituitary-adrenocortical (HPA) axis function in mania, particularly in mixed states. We therefore investigated HPA function and its relationship to clinical state in 19 hospitalized manic patients meeting Schedule for Affective Disorders and Schizophrenia - Research Diagnostic Criteria for acute manic episodes, compared patients with and without a mixed presentation, and examined correlations between HPA activity and behavior. Data were available… CONTINUE READING


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