Hypothalamic-pituitary-adrenal suppression after short-term dexamethasone therapy for oral surgical procedures.

@article{Williamson1980HypothalamicpituitaryadrenalSA,
  title={Hypothalamic-pituitary-adrenal suppression after short-term dexamethasone therapy for oral surgical procedures.},
  author={Lyn Williamson and E L Lorson and D B Osbon},
  journal={Journal of oral surgery},
  year={1980},
  volume={38 1},
  pages={20-8}
}
Ten patients were given dexamethasone therapy for prevention of postoperative complications after oral surgical procedures. The hypothalamic-pituitary-adrenal response of the patients was measured by their response to a single-dose metyrapone test. A significant difference was found between preoperative values of 11-deoxycortisol and values three days postoperatively. No difference was found when comparing preoperative values of 11-deoxycortisol with values seven days postoperatively. There… CONTINUE READING
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