Hypothalamic-pituitary-adrenal axis suppression and inhaled corticosteroid therapy. 1. General principles.


The safety of long-term inhaled corticosteroid therapy at commonly prescribed doses is an issue of growing concern to physicians and international regulatory bodies. This is so because long-term use of these drugs has become the mainstay of chronic asthma management and their introduction now is widely recommended in official treatment guidelines at the… (More)


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