Hypothalamic-pituitary-adrenal axis response to sustained stress after major burn injury in children.

@article{Palmieri2006HypothalamicpituitaryadrenalAR,
  title={Hypothalamic-pituitary-adrenal axis response to sustained stress after major burn injury in children.},
  author={Tina Palmieri and Seymour Levine and Nancy Schonfeld-Warden and M Shay O'mara and David G. Greenhalgh},
  journal={Journal of burn care & research : official publication of the American Burn Association},
  year={2006},
  volume={27 5},
  pages={742-8}
}
The hypothalamic-pituitary-adrenal (HPA) axis is responsible for stress response after injury, yet its function after severe burn injury in children is unclear. The purpose of this study was to define the effects of burn injury on the HPA axis and to evaluate the utility of total serum cortisol in measuring adrenal function in children with major burns in the 2 months after injury. Children ages 0 to 17 years who were admitted within 72 hours to our pediatric burn center with 20% TBSA or… CONTINUE READING

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