Hypothalamic orexin-A-immunpositive neurons express Fos in response to central glucopenia.

@article{Briski2001HypothalamicON,
  title={Hypothalamic orexin-A-immunpositive neurons express Fos in response to central glucopenia.},
  author={Karen P Briski and Paul William Sylvester},
  journal={Neuroreport},
  year={2001},
  volume={12 3},
  pages={531-4}
}
Reports that glucose antimetabolite treatment elicits hyperphagia and hyperglycemia suggest that decreased oxidation of this energy substrate elicits compensatory responses that enhance cellular fuel availability. Neurons the lateral hypothalamic area (LHA) synthesize the orectic neuropeptide, orexin-A (ORX-A). The present study evaluated the functional responsiveness of orexinergic neurons to glucopenia by investigating whether these cells express the genomic regulatory protein, Fos, in… CONTINUE READING
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