Hypothalamic inhibition of rat dorsal horn neuronal responses to noxious skin heating.

@article{Carstens1986HypothalamicIO,
  title={Hypothalamic inhibition of rat dorsal horn neuronal responses to noxious skin heating.},
  author={Earl E. Carstens},
  journal={Pain},
  year={1986},
  volume={25 1},
  pages={95-107}
}
The responses of single lumbar dorsal horn neurons to noxious radiant heat stimuli (42-54 degrees C, 10 sec, 1/2 min) applied to glabrous hind paw skin were recorded in rats anesthetized with sodium pentobarbital. Unit responses to 50 or 52 degrees C stimuli were constant over time and were consistently and powerfully inhibited during bipolar stimulation (three 100 msec trains/sec at 100 Hz, 200 microA) in the medial hypothalamus. Inhibition was also evoked by stimulation in medial and… CONTINUE READING