Hypothalamic hormone interaction in acromegaly.

  title={Hypothalamic hormone interaction in acromegaly.},
  author={Antonio G{\'o}mez-Pan and W Michael G Tunbridge and A Duns and Reginald Hall and G. Michael Besser and David H. Coy and Andrew V Schally and Abba J. Kastin},
  journal={Clinical endocrinology},
  volume={4 5},
The growth hormone response to the administration of the currently available synthetic hypothalamic hormones was assessed in eleven patients with acromegaly. Eight of them showed a positive GH response to thyrotrophin releasing hormone and three showed no response. The GH response to TRH was shown to be unrelated to the thyrotrophin response to TRH. The GH response to TRH was inhibited by the administration of growth hormone release inhibiting hormone. Luteinizing hormone/follicle stimulating… CONTINUE READING