Hypothalamic gene expression is altered in underweight but obese juvenile male Sprague-Dawley rats fed a high-energy diet.

@article{Archer2004HypothalamicGE,
  title={Hypothalamic gene expression is altered in underweight but obese juvenile male Sprague-Dawley rats fed a high-energy diet.},
  author={Zoe Anne Archer and Dr. V. Rayner and Julian G Mercer},
  journal={The Journal of nutrition},
  year={2004},
  volume={134 6},
  pages={
          1369-74
        }
}
The incidence of obesity, with its associated health risks, is on the increase throughout the western world affecting all age groups, including children. The typical western diet is high in fat and sugar and low in complex carbohydrates. This study looks at the effects of feeding an equivalent high-energy (HE) diet to growing rats. Juvenile male Sprague-Dawley rats that were fed an HE (18.9 kJ/g) diet starting approximately 10 d after weaning gained less weight than littermates fed a… CONTINUE READING
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