Hypothalamic gene expression in long-term fasted rats: relationship with body fat.

@article{Bertile2003HypothalamicGE,
  title={Hypothalamic gene expression in long-term fasted rats: relationship with body fat.},
  author={Fabrice Bertile and Hugues Oudart and François Criscuolo and Yvon le Maho and Thierry Raclot},
  journal={Biochemical and biophysical research communications},
  year={2003},
  volume={303 4},
  pages={1106-13}
}
Many hypothalamic neuropeptides are involved in the regulation of energy homeostasis and feeding behavior. We have investigated whether and to what extent neuropeptide Y (NPY), agouti-related protein (AGRP), melanin-concentrating hormone (MCH), and prepro-orexin (prepro-OX) as well as pro-opiomelanocortin (POMC) and cocaine and amphetamine-regulated transcript (CART) mRNA levels are affected in rat hypothalamus. An experimental model of long-term fasting rat characterized by three metabolic… CONTINUE READING