Hypothalamic Nesfatin-1 Stimulates Sympathetic Nerve Activity via Hypothalamic ERK Signaling.

@article{Tanida2015HypothalamicNS,
  title={Hypothalamic Nesfatin-1 Stimulates Sympathetic Nerve Activity via Hypothalamic ERK Signaling.},
  author={Mamoru Tanida and Hitoshi Gotoh and Naoki Yamamoto and Mofei Wang and Yuhichi Kuda and Yasutaka Kurata and Masatomo Mori and Toshishige Shibamoto},
  journal={Diabetes},
  year={2015},
  volume={64 11},
  pages={3725-36}
}
Nesfatin-1 acts on the hypothalamus and regulates the autonomic nervous system. However, the hypothalamic mechanisms of nesfatin-1 on the autonomic nervous system are not well understood. In this study, we found that intracerebroventricular (ICV) administration of nesfatin-1 increased the extracellular signal-regulated kinase (ERK) activity in rats… CONTINUE READING