Hypothalamic Mitochondrial Dysfunction as a Target in Obesity and Metabolic Disease

@inproceedings{Cuarro2018HypothalamicMD,
  title={Hypothalamic Mitochondrial Dysfunction as a Target in Obesity and Metabolic Disease},
  author={Juan Cu{\~n}arro and Sabela Casado and Javier Lugilde and S Jos{\'e} Joimer Tovar},
  booktitle={Front. Endocrinol.},
  year={2018}
}
Mitochondria are important organelles for the adaptation to energy demand that play a central role in bioenergetics metabolism. The mitochondrial architecture and mitochondrial machinery exhibits a high degree of adaptation in relation to nutrient availability. On the other hand, its disruption markedly affects energy homeostasis. The brain, more specifically the hypothalamus, is the main hub that controls energy homeostasis. Nevertheless, until now, almost all studies in relation to… CONTINUE READING
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