Hypotensive effects of nifedipine in patients with primary hyperparathyroidism: case reports.

Abstract

Nifedipine was administered orally to 2 patients with primary hyperparathyroidism before and after parathyroidectomy. The operation lowered serum calcium concentration and parathyroid hormone but did not alter plasma renin activity, plasma aldosterone concentration, and serum magnesium. The hypotensive effects of nifedipine were markedly enhanced with the decrease in serum calcium concentration following parathyroidectomy. Thus, the level of serum calcium concentration may modulate the hypotensive effect of nifedipine in humans.

Cite this paper

@article{Takata1989HypotensiveEO, title={Hypotensive effects of nifedipine in patients with primary hyperparathyroidism: case reports.}, author={Yutaka Takata and Shuichi Takishita and Tetsuya Koga and Yasushi Nakao and Kunihiro Okamura and Takashi Yao and Kaoru Takemura and Masatoshi Fujishima}, journal={Angiology}, year={1989}, volume={40 12}, pages={1079-82} }