Hypotension caused by L-dopa.

  title={Hypotension caused by L-dopa.},
  author={Donald B. Calne and James Brennan and Alexander S.D. Spiers and Gerald M Stern},
  journal={British medical journal},
  volume={1 5694},
In 20 patients with idiopathic Parkinsonism maximum tolerated doses of L-dopa were found to induce a mean reduction in blood pressure (erect systolic) of 19.3 mm.Hg, without any significant change in pulse rate. This hypotension may be due to dopamine, acting on adrenergic nerve endings or on the central nervous system itself.