Hyposplenism: a comprehensive review. Part I: basic concepts and causes.

@article{William2007HyposplenismAC,
  title={Hyposplenism: a comprehensive review. Part I: basic concepts and causes.},
  author={Basem Magdy William and Gino R Corazza},
  journal={Hematology},
  year={2007},
  volume={12 1},
  pages={1-13}
}
Hyposplenism is not a rare condition and can complicate a remarkable number of illnesses. The two most time-honored diseases associated with the development of hyposplenism are sickle cell anemia and celiac disease. Hyposplenism is relatively easy to recognize by typical changes observed on the peripheral blood smear; including Howell-Jolly bodies, monocytosis, lymphocytosis, and increased platelet counts. Diagnosis can be confirmed by pitted RBC counts or 99Tc-labelled radiocolloid scan of the… CONTINUE READING
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