Hypopituitarism following radiation therapy of pituitary adenomas.

  title={Hypopituitarism following radiation therapy of pituitary adenomas.},
  author={Peter J. Snyder and B F Fowble and Norman J. Schatz and Peyer J Savino and Thomas A. Gennarelli},
  journal={The American journal of medicine},
  volume={81 3},
Pituitary function was evaluated before and after supervoltage radiotherapy for a pituitary adenoma in 35 patients; 22 had had prior surgical treatment, and 13 had not. For comparison, pituitary function was also followed concurrently in another 10 patients whose pituitary adenomas were treated surgically, but who did not receive subsequent radiotherapy. Following radiotherapy, deficiencies of adrenal, thyroid, and gonadal function developed in 67, 55, and 67 percent of the patients who had… CONTINUE READING

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