Hyponatremia associated with overhydration in U.S. Army trainees.

@article{OBrien2001HyponatremiaAW,
  title={Hyponatremia associated with overhydration in U.S. Army trainees.},
  author={Karen K. O'Brien and Scott Montain and William P. Corr and Michael N. Sawka and Joseph J. Knapik and Stephen C. Craig},
  journal={Military medicine},
  year={2001},
  volume={166 5},
  pages={
          405-10
        }
}
This report describes a series of hyponatremia hospitalizations associated with heat-related injuries and apparent over-hydration. Data from the U.S. Army Inpatient Data System were used to identify all hospitalizations for hyposmolality/hyponatremia from 1996 and 1997. Admissions were considered as probable cases of overhydration hyponatremia if this was the only, or primary, diagnosis or if it was associated with any heat-related diagnosis. Seventeen medical records were identified, and the… 

Figures and Tables from this paper

Hyponatremia among runners in the Boston Marathon.

Considerable weight gain while running, a long racing time, and body-mass-index extremes were associated with hyponatremia, whereas female sex, composition of fluids ingested, and use of nonsteroidal antiinflammatory drugs were not.

Clinical characteristics and outcomes of hyponatraemia associated with oral water intake in adults: a systematic review

Water intoxication is associated with significant morbidity and mortality and requires daily intake to substantially exceed population-based recommendations and the limitations of this analysis are the low quality and high risk of bias of the included studies.

Treatment of hyponatremia

Planning therapy to achieve a 6 mEq/l daily increase in the serum sodium concentration can avoid iatrogenic brain damage by staying well clear of correction rates that are harmful, and Conservative correction goals are wise.

Collapse in the Heat - From Overhydration to the Emergency Room - Three Cases of Exercise-Associated Hyponatremia Associated with Exertional Heat Illness.

Limiting fluid availability during field or recreational events of up to 3 h may prevent symptomatic hyponatremia while limiting significant dehydration, and obtaining point-of-care serum sodium may improve recognition of hypon atremia and guide management for the patient with suspected heat illness and hyponatsmia.

Postmortem diagnosis of hyponatremia: case report and literature review

A case of fatal water intoxication in a psychiatric patient who underwent medicolegal investigations, including postmortem biochemistry, was chosen as a starting point to a literature review of deaths by hyponatremia that may be encountered in the forensic setting.

Hyponatremia in Endurance Athletes

The purpose of this paper was to identify the relationship between hyponatremia, or water intoxication, and endurance athletes and to educate allied health professionals, coaches, and athletes about this potentially fatal problem.

A Case of Water Intoxication with Prolonged Hyponatremia Caused by Excessive Water Drinking and Secondary SIADH

Saline infusion and an initial administration of furosemide in addition to dexamethasone as treatments for the patient's brain edema successfully improved his laboratory data and clinical signs by the 3rd hospital day, and he was returned to the facility without physical or psychiatric abnormalities on the 6th day.

Exercise-associated hyponatremia.

Marathon related death due to brainstem herniation in rehydration-related hyponatraemia: a case report

Given the frequency of hyponatraemia in marathon runners, and the non-specific symptoms, how a simple screening test such as funduscopy may help to identify those who require urgent neuroimaging is discussed.

Life-threatening hyponatremia in marathon runners: The Varon-Ayus syndrome revisited

Marathon runners are at particular risk of developing a syndrome which consists of severe hyponatremia, pulmonary edema and cerebral edema as originally described by Varon and Ayus.
...

References

SHOWING 1-10 OF 23 REFERENCES

Death from hyponatremia as a result of acute water intoxication in an Army basic trainee.

The first known death of an Army basic trainee as a result of acute water intoxication is reported, and the misinterpretation of his symptoms as those of dehydration and heat injury led to continued efforts at oral hydration until catastrophic cerebral and pulmonary edema developed.

Water: can the endurance athlete get too much of a good thing?

Glycerol hyperhydration: hormonal, renal, and vascular fluid responses.

Antidiuretic hormone concentrations (ADH) were significantly reduced from prehyperhydration levels during both hyperhydration trials but tended to rise during GI compared with WI at the very time urine flow and free water clearance differences were also evident, suggesting that ADH may, in part, be responsible for glycerol's effectiveness.

Heat acclimation in cystic fibrosis.

Before and after acclimation, exercise-heat sessions resulted in significant decreases in serum [Cl-] in CF patients and normal controls, and both groups had significant renal Na+ conservation after exercise on both days.

Water Intoxication: A Possible Complication During Endurance Exercise

Four athletes developed water intoxication (hyponatremia) during endurance events lasting more than 7 hours and when advised to drink less during prolonged exercise, three of the athletes have subsequently completed prolonged endurance events uneventfully.

Influence of the emetic reflex on vasopressin release in man.

These studies indicate that stimulation of the emetic reflex results in AVP-release in man and rat, and indicates that Nausea-mediated AVP release supervenes over concomitant osmolar or pharmacologic inhibition.

Fluid replacement recommendations for training in hot weather.

The development and validation of revised fluid replacement guidelines for hot weather training are summarized and the end product is an easy-to-read table that provides the user with the appropriate hourly work time and fluid intake to support work during hot weatherTraining.

Acute water intoxication as a complication of urine drug testing in the workplace.

It is concluded that risk factors for acute water intoxication include intake of more than 1 L of water and impaired urine dilution and in a recently drug-tested worker, symptoms of cerebral dysfunction should suggest the possibility of water intoxication.

Influence of hydration level and body fluids on exercise performance in the heat.

Hyperhydration, or body fluid excess, does not seem to provide a clear advantage during exercise-heat stress, but will delay the development of hypohydration.

Fluid replacement during sustained activity in the heat: nutrient solution vs. water.

Data indicate that during 13 h of sustained activity in a hot environment, the nutrient solution and water provided similar thermoregulatory and hydrational benefits.