Hypolipidemic effect of mannans from C. albicans serotypes a and B in acute hyperlipidemia in mice.

  title={Hypolipidemic effect of mannans from C. albicans serotypes a and B in acute hyperlipidemia in mice.},
  author={Tatyana A. Korolenko and Thomas P. Johnston and Eva Machov{\'a} and Nataliya P. Bgatova and A. P. Lykov and Natalya V. Goncharova and Zuzana Ne{\vs}{\vc}{\'a}kov{\'a} and Alexandra B Shintyapina and I. V. Maiborodin and O L Karmatskikh},
  journal={International journal of biological macromolecules},
  volume={107 Pt B},

Figures and Tables from this paper

Hypolipidemic Effects of β-Glucans, Mannans, and Fucoidans: Mechanism of Action and Their Prospects for Clinical Application
This review will present up-to-date information regarding experimental hypolipidemic polysaccharide compounds that hold promise for medicine regarding β-glucans and Phagocyte-specific chitotriosidase in humans.
Trehalose Activates Hepatic and Myocardial Autophagy and Has Anti-Inflammatory Effects in db/db Diabetic Mice
The autophagyactivation by trehalose had several positive effects on the heart and liver of db/db mice; therefore, lipophagy activation seems to be a promising therapy for diabetes.
Mannans: An overview of properties and application in food products.
Extraction of crude Mannan oligosaccharides from yeast and their uses
This review aims to emphasize the importance of mannan oligosaccharides, obtained from various resources especially from yeasts. Attractive features of mannan polysaccharides have had influenced the
Effect of mesenchymal stem cells cultivation with erythropoietin on their morphofunctional properties
Cultivation of MSCs with erythropoietin increases the resistance of cells to adverse microenvironment factors, and contributes to an increase in the expression of the main surface molecules that characterize the cells belonging to true M SCs.
Lysosomotropic Features and Autophagy Modulators among Medical Drugs: Evaluation of Their Role in Pathologies
The present review summarizes current knowledge on the lysosomotropic features of medical drugs, as well as autophagy inducers, and their role in pathological processes.
Glucan and Mannan—Two Peas in a Pod
This review focused on the biological properties of mannan and glucan, the two most and best-studied polysaccharides in the area of nutrition and medicine.
Monosaccharide induced temporal delay in cholesterol self-aggregation.
Self-assembly of cholesterol (CHL) is infamous for its diverse deleterious effects on human health. Clinical research over several decades indicates that a diet rich in CHL typically leads to
The development of a complex technique for the extraction and purification of polysaccharides from birch leaves (Betula pendula Roth.,Betula pubescens Ehrh.) (PSfB) was the purpose of this study. The


Innate Immune Proteins C1q and Mannan-Binding Lectin Enhance Clearance of Atherogenic Lipoproteins by Human Monocytes and Macrophages
A novel pathway in which C1q and MBL influence removal and metabolism of atherogenic forms of LDL in the early stages of atherosclerosis is suggested.
Serum cystatin C and chitotriosidase in acute P-407 induced dyslipidemia: Can they serve as potential early biomarkers for atherosclerosis?
Macrophage-Specific Expression of Mannose-Binding Lectin Controls Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice
These results are the first to show that MBL is abundantly present and locally produced during early atherogenesis, and local MBL expression, by myeloid cells, is shown to critically control development of atherosclerotic lesions.
P-407-induced Mouse Model of Dose-controlled Hyperlipidemia and Atherosclerosis: 25 Years Later
It is strongly suggested that the P-407–induced hyperlipidemic mouse model represents a convenient, inexpensive, and well-documented alternative mouse model with which to study cardiovascular heart disease arising from dyslipidemia and atherosclerosis.
Side-chain structure of cell surface polysaccharide, mannan, affects hypocholesterolemic activity of yeast.
The results show that the side-chain length and phosphate contents of mannan affect hypocholesterolemic activity, and K. marxianus YIT 8292 had shorter alpha-(1,2)-linked oligomannosyl side chains and lower phosphate content in mannan than S. cerevisiae.
Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity.
Man has been found to produce highly conserved chitinases. The most prominent is the phagocyte-derived chitotriosidase, the plasma levels of which are markedly elevated in some pathological
Role of macrophage activation in the lipid metabolism of postprandial triacylglycerol-rich lipoproteins
It is concluded that inflammation causes a greater increase in the accumulation of neutral lipids than ppTGRL in macrophages, and that this effect is related to modulation of PL metabolism and possibly also CH synthesis.
Zymosan-mediated inflammation impairs in vivo reverse cholesterol transport[S]
The study supports the notion that RCT impairment is one of the mechanisms for the increased atherosclerotic burden observed in inflammatory conditions and suggests that zymosan impairs in vivo RCT primarily by decreasing macrophage-derived cholesterol entering the plasma, with minimal additional blocks downstream.