Hypolipidemic effect of fenugreek seeds is mediated through inhibition of fat accumulation and upregulation of LDL receptor.

@article{Vijayakumar2010HypolipidemicEO,
  title={Hypolipidemic effect of fenugreek seeds is mediated through inhibition of fat accumulation and upregulation of LDL receptor.},
  author={Maleppillil Vavachan Vijayakumar and Vimal Mohan Pandey and Gyan Chandra Mishra and Manoj Kumar Bhat},
  journal={Obesity},
  year={2010},
  volume={18 4},
  pages={667-74}
}
Fenugreek (Trigonella foenum-graecum) seeds, used as a condiment, are documented for health benefits including amelioration of abnormalities in lipid homeostasis due to its hypolipidemic properties. However, molecular mechanisms underlying the hypolipidemic effect of fenugreek seeds remain obscure. In this study, hypolipidemic effect of a novel thermostable extract of fenugreek seeds (TEFS) was evaluated in vitro by employing differentiating and differentiated 3T3-L1 cells, and HepG2 cells… CONTINUE READING

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