Hypolipidemic and antioxidant activities of polysaccharides from Rosae Laevigatae Fructus in rats.

@article{Yu2013HypolipidemicAA,
  title={Hypolipidemic and antioxidant activities of polysaccharides from Rosae Laevigatae Fructus in rats.},
  author={Chen-huan Yu and Xiao-yan Dai and Qin Chen and Jia-Na Zang and Li-li Deng and Yue-Huan Liu and Hua-zhong Ying},
  journal={Carbohydrate polymers},
  year={2013},
  volume={94 1},
  pages={56-62}
}
Two major fractions (RLP-1 and RLP-2) were obtained by purifying the crude polysaccharides extracted from a traditional Chinese herb Rosae Laevigatae Fructus. The average molecular weight of RLP-1 and RLP-2 was 21.5 kDa and 16.1 kDa, respectively. Monosaccharide analysis indicated that RLP-1 was composed of xylose, mannose and galactose in the molar ratio of 1:11:8, while RLP-2 was only a glucan. Oral administration of RLP-1 could significantly decrease levels of serum total cholesterol (TC… CONTINUE READING

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