Hypolipidemic Effects of Alkaloids from Rhizoma Coptidis in Diet-Induced Hyperlipidemic Hamsters.

  title={Hypolipidemic Effects of Alkaloids from Rhizoma Coptidis in Diet-Induced Hyperlipidemic Hamsters.},
  author={K. He and Shuming Kou and Zongyao Zou and Yinran Hu and M. Feng and B. Han and Xuegang Li and Xiaoli Ye},
  journal={Planta medica},
  volume={82 8},
  • K. He, Shuming Kou, +5 authors Xiaoli Ye
  • Published 2016
  • Chemistry, Medicine
  • Planta medica
  • This study was conducted to evaluate the antihyperlipidemic activity of five major alkaloids in Rhizoma Coptidis using high-fat- and high-cholesterol-induced hyperlipidemic hamsters. Hyperlipidemic hamsters were treated with coptisine, berberine, jatrorrhizine, palmatine, epiberberine, and total Rhizoma Coptidis alkaloids with a dose of 46.7 mg/kg × day for 140 days. Serum total cholesterol, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and total bile… CONTINUE READING
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