• Corpus ID: 3829645

Hypolipidemic Effect of Pleurotus djamor var. roseus in Experimentally Induced Hypercholesteromic Rats.

@inproceedings{Jegadeesh2014HypolipidemicEO,
  title={Hypolipidemic Effect of Pleurotus djamor var. roseus in Experimentally Induced Hypercholesteromic Rats.},
  author={Raman Jegadeesh and Nanjian Raaman and Lakshmanan Hariprasath and Venkat Ramesh and Ramasundaram Srikumar},
  year={2014}
}

• R. Jegadeesh, N. Raaman, +2 authors R. Srikumar
• Published 2014
• Biology

Hypercholesteremia is one of the risk factors for coronary artery disease. Mushrooms are low calorie food with very little fat and are highly suitable for obese persons. The present study highlights the efficacy of edible mushroom Pleurotus djamor var. roseus extracts on total cholesterol, low density lipoprotein (LDL), very low density lipoprotein (VLDL), High density lipoprotein (HDL) and free fatty acid in experimentally induced hypercholesteromic rats. Five group of rats were employed which includes control, mushroom extract, hypercholesterolemia rats (4 % cholesterol + 1% cholic acid + egg yolk), hypercholesterolemia rats treated with Mevinolin and hypercholesterolemia rats with pretreatment of mushroom extract and each group includes six animals. Results from the present study showed that significant increase in the total cholesterol, LDL, VLDL and free fatty acid observed in hypercholesteromic feed rats were significantly reduced in mushroom extract treated hypercholesteromic rats. These results suggest that mushroom supplement provided health benefits by acting on the lipid profile in hypercholesterolemic rats. Kewwords: P. djamor var. roseus, Cholesterol, Lipid profile, Mevinolin