Hypoglycemic effects of lactucin-8-O-methylacrylate of Parmentiera edulis fruit.

@article{Prez2000HypoglycemicEO,
  title={Hypoglycemic effects of lactucin-8-O-methylacrylate of Parmentiera edulis fruit.},
  author={Rodolfo M P{\'e}rez and Cirilo P{\'e}rez and Miguel Angel Zavala and Salud P{\'e}rez and Hector Hernandez and F Lagunes},
  journal={Journal of ethnopharmacology},
  year={2000},
  volume={71 3},
  pages={391-4}
}
Hypoglycemic activity-guided fractionation together with chemical analysis led to the isolation of one guaianolide (lactucin-8-O-methylacrylate) from the chloroform extract of the dried fruits of Parmentiera edulis. Identification was based on spectroscopic methods. The compounds lowers blood sugar levels after administration to alloxan-diabetic mice.