Hypoglycemic and antioxidant effects of honey supplementation in streptozotocin-induced diabetic rats.

@article{Erejuwa2010HypoglycemicAA,
  title={Hypoglycemic and antioxidant effects of honey supplementation in streptozotocin-induced diabetic rats.},
  author={Omotayo Owomofoyon Erejuwa and Sunil Gurtu and Siti Amrah Sulaiman and Mohd Suhaimi Ab Wahab and Kuttulebbai Nainamohamed Salam Sirajudeen and Md Salzihan Md Salleh},
  journal={International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition},
  year={2010},
  volume={80 1},
  pages={74-82}
}
OBJECTIVES Oxidative stress plays a crucial role in the development of diabetic complications. The aims of this study were to investigate whether honey could reduce hyperglycemia and ameliorate oxidative stress in kidneys of streptozotocin-induced diabetic rats. METHODS Diabetes was induced by a single dose of STZ (60 mg/kg; i. p.). Diabetic rats were randomly grouped and administered distilled water (0.5 mL/day) and honey (0.2 g/kg/day, 1.2 g/kg/day and 2.4 g/kg/day) by oral gavage for four… CONTINUE READING
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