Corpus ID: 12148291

Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root.

  title={Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root.},
  author={Bondada Andallu and B. J. Radhika},
  journal={Indian journal of experimental biology},
  volume={38 6},
Hypoglycemic, diuretic and hypocholesterolemic effects of roots of W. somnifera (ashvagandha) were assessed on human subjects. Six mild NIDDM subjects and six mild hypercholesterolemic subjects were treated with the powder of roots of W. somnifera for 30 days. Suitable parameters were studied in the blood and urine samples of the subjects along with dietary pattern before and at the end of treatment period. Decrease in blood glucose was comparable to that of an oral hypoglycemic drug… Expand
Hypoglycaemic and Hypolipidaemic Effects of Withania somnifera Root and Leaf Extracts on Alloxan-Induced Diabetic Rats
Treatment of the diabetic rats withWSREt, WSLEt and glibenclamide restored the changes of the above parameters to their normal level after eight weeks of treatment, indicating that WSREt and WSLET possess hypoglycaemic and hypolipidaemic activities in alloxan-induced diabetes mellitus (DM) rats. Expand
Hypoglycaemic effects of the aqueous seed extract of Hunteria umbellata in normoglycaemic and glucose-and nicotine-induced hyperglycaemic rats
Dry seeds of the plant, Hunteria umbellata K. Schum (family: Apocynaceae), are highly valued in African traditional medicine in the treatment of various human diseases, including diabetes mellitusExpand
Effects of combination of Shilajit extract and Ashwagandha (Withania somnifera) on fasting blood sugar and lipid profile.
At the end of the therapy period, it was found that the drug had considerably reduced symptoms related to diabetes, average fasting blood sugar and lipid profile. Expand
Withania somnifera shows a protective effect in monocrotaline-induced pulmonary hypertension
This study demonstrated that W. somnifera significantly protected against MCT-induced PH due to its antioxidant, anti-inflammatory, pro-apoptotic, and cardioprotective properties. Expand
Effect of Dianex, a herbal formulation on experimentally induced diabetes mellitus
Dianex, a polyherbal formulation consisting of the aqueous extracts of Gymnema sylvestre, Eugenia jambolana, Momordica charantia Azadirachta indica, Cassia auriculata, Aegle marmelose, WithaniaExpand
Hypoglycemic activity of withanolides and elicitated Withania somnifera.
Withania somnifera, known in India as Asghawhanda, is used traditionally to treat many medical problems including diabetes and has demonstrated therapeutic activity in various animal models as wellExpand
Influence of Withania somnifera on 24 h oscillations of biomarkers in gentamicin induced nephrotoxicity
It is concluded that W. somnifera alter the circadian variations directly with its valuable bioactive compounds, which could pave a way for future investigation for therapeutic approach. Expand
A Review on Pharmacological Profile of Withania somnifera (Ashwagandha).
Research indicates ashwagandha possesses antioxidant, anxiolytic, adaptogen, memory enhancing, antiparkinsonian, antivenom, antiinflammatory, antitumor properties, which are very encouraging and indicate this herb should be studied more extensively to confirm these results and reveal other potential therapeutic effects. Expand
Hypoglycaemic effects of the herb ashwagandha, Withania somnifera, using in vitro assays and its potential in preventing stress induced hyperglycaemia in rat (in vivo) were studied. W. somniferaExpand
Phytochemical Study of the Plant Withania somnifera against Various Diseases
Withania somnifera or ashwagandha is commonly used as a folk medicine for the treatment of various diseases and acts as an adaptogen that exerts a strong immunostimulatory and an anti-stress agent. Expand


Subacute toxicity study of the combination of ginseng (Panax ginseng) and ashwagandha (Withania somnifera) in rats: a safety assessment.
There was significant increase in body weight, food consumption and liver weight, and improved hematopoiesis was observed, and subacute toxicity studies in rats did not reveal any toxicity. Expand
Effect of Trasina, an Ayurvedic herbal formulation, on pancreatic islet superoxide dismutase activity in hyperglycaemic rats.
Transina (TR), an Ayurvedic herbal formulation comprising of Withania somnifera, Tinospora cordifolia, Eclipta alba, Ocimum sanctum, Picrorrhiza kurroa and shilajit had little per se effect on blood sugar concentrations and islet SOD activity in euglycaemic rats, in the doses of 100 and 200 mg/kg. Expand
Efficacy of an ayurvedic formulation in rheumatoid arthritis: A double-blind, placebo-controlled, cross-over study
Treatment with the indigenous formulation for the period of 3 months produced significantly greater relief of pain, decreased morning stiffness, decrease in Ritche articular index and joint score and side effects observed did not necesitate withdrawal of treatment. Expand
Studies on the hypotensive effect of high potassium intake in patients with essential hypertension.
The results suggest that the hypotensive effect of high potassium intake may be caused by reduction of body fluid volume via augmentation of Na excretion. Expand
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.
A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented and comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99. Expand
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