Hypoglycaemia following diabetes remission in patients with 6q24 methylation defects: expanding the clinical phenotype


To the Editor: Methylation defects at chromosome 6q24 are the most common cause of transient neonatal diabetes mellitus (TNDM), accounting for 70% of all cases [1, 2]. Those affected have impaired insulin secretion, as shown by a very low birthweight (median below the first centile) and a diagnosis of diabetes usually at or shortly after birth (range 0–4… (More)
DOI: 10.1007/s00125-012-2766-z


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