Hypoglycaemia: brain neurochemistry and neuropathology.

  title={Hypoglycaemia: brain neurochemistry and neuropathology.},
  author={Roland N. Auer and Bo K. Siesj{\"o}},
  journal={Bailliere's clinical endocrinology and metabolism},
  volume={7 3},
The widespread use of insulin and oral hypoglycaemic agents has increased the incidence of hypoglycaemic brain damage due to accidental, suicidal, or homicidal overdose. Hypoglycaemia is capable of damaging the brain in the face of intact cardiac function, but neuronal necrosis occurs only when the electroencephalogram (EEG) becomes isoelectric. Neurochemical changes are distinct from ischaemia, and cerebral blood flow is actually increased, in contrast to cerebral ischaemia. Salient… CONTINUE READING
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