Hypogammaglobulinemia and rheumatic disease.

  title={Hypogammaglobulinemia and rheumatic disease.},
  author={Agnes H Lee and Arnold I. Levinson and Harold R. Schumacher},
  journal={Seminars in arthritis and rheumatism},
  volume={22 4},
Primary hypogammaglobulinemia describes a heterogeneous group of immunoglobulin disorders mainly composed of X-linked agammaglobulinemia, common variable immunodeficiency, and selective immunoglobulin (Ig) A deficiency. The most serious problems are related to recurrent infections with high-grade encapsulated bacteria. However, a wide variety of rheumatologic disorders also occur in association with hypogammaglobulinemic states. Septic arthritis with usual bacterial pathogens such as… CONTINUE READING


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