Hypofrontality in men with first-episode psychosis.

  title={Hypofrontality in men with first-episode psychosis.},
  author={Vicente Molina and Javier Sanz and S Reig and Ray Martinez and Fernando Sarramea and Rafael Luque and Carlos Benito and J D Gispert and Javier Pascau and Manuel Desco},
  journal={The British journal of psychiatry : the journal of mental science},
BACKGROUND Decreased metabolic activity in the prefrontal cortex during cognitive activation is a recurrent finding and a likely functional marker of schizophrenia. AIMS To investigate the occurrence of hypofrontality in patients with first-episode psychosis, with or without evolution to schizophrenia. METHOD We used fluorodeoxyglucose positron emission tomography during the performance of an attention task and magnetic resonance imaging to study the dorsolateral prefrontal region in 13 men… CONTINUE READING

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