Hypofractionated high-dose proton beam therapy for stage I non-small-cell lung cancer: preliminary results of a phase I/II clinical study.

@article{Hata2007HypofractionatedHP,
  title={Hypofractionated high-dose proton beam therapy for stage I non-small-cell lung cancer: preliminary results of a phase I/II clinical study.},
  author={M. Hata and Koichi Tokuuye and Kenji Kagei and Shinji Sugahara and Hidetsugu Nakayama and Nobuyoshi Fukumitsu and Takayuki Hashimoto and Masashi Mizumoto and Kiyoshi Ohara and Yasuyuki Akine},
  journal={International journal of radiation oncology, biology, physics},
  year={2007},
  volume={68 3},
  pages={786-93}
}
PURPOSE To present treatment outcomes of hypofractionated high-dose proton beam therapy for Stage I non-small-cell lung cancer (NSCLC). METHODS AND MATERIALS Twenty-one patients with Stage I NSCLC (11 with Stage IA and 10 with Stage IB) underwent hypofractionated high-dose proton beam therapy. At the time of irradiation, patient age ranged from 51 to 85 years (median, 74 years). Nine patients were medically inoperable because of comorbidities, and 12 patients refused surgical resection… CONTINUE READING
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