Hypofractionated high-dose irradiation for the treatment of malignant astrocytomas using simultaneous integrated boost technique by IMRT.

@article{Iuchi2006HypofractionatedHI,
  title={Hypofractionated high-dose irradiation for the treatment of malignant astrocytomas using simultaneous integrated boost technique by IMRT.},
  author={Toshihiko Iuchi and Kazuo Hatano and Yuichiro Narita and Takashi Kodama and Tomohiro Yamaki and Katsunobu Osato},
  journal={International journal of radiation oncology, biology, physics},
  year={2006},
  volume={64 5},
  pages={1317-24}
}
PURPOSE We evaluated the clinical significance of hypofractionated high-dose irradiation using simultaneous integrated boost technique with intensity-modulated radiation therapy (IMRT) for the treatment of malignant astrocytomas (MAs). METHODS AND MATERIALS Twenty-five patients with MAs were treated by IMRT. Three layered planning target volumes (PTVs) were contoured. PTV-1 was the area of enhanced lesion with 5-mm margin; PTV-2 was the area with 15-mm margin surrounding the PTV-1; PTV-3 was… CONTINUE READING