Hypodiploid, pseudodiploid, and normal karyotypes prevail in cytogenetic studies of medullary carcinomas of the thyroid and metastatic tissues.

@article{WursterHill1990HypodiploidPA,
  title={Hypodiploid, pseudodiploid, and normal karyotypes prevail in cytogenetic studies of medullary carcinomas of the thyroid and metastatic tissues.},
  author={Doris H. Wurster-Hill and Olive S. Pettengill and Walter W. Noll and S H Gibson and T Brinck-Johnsen},
  journal={Cancer genetics and cytogenetics},
  year={1990},
  volume={47 2},
  pages={227-41}
}
Medullary carcinoma of the thyroid (MCT), often a dominantly inherited neoplasm, derived from intrathyroid C-cells of neural crest origin, is one of the solid tumors least studied cytogenetically. The cells are difficult to grow in culture, only two cell lines having ever been established. Cytogenetic studies of only 5 tumors have been reported previously. In this paper we report on the cytogenetic analyses of 8 specimens of primary and/or metastatic MCT tumor tissue from 6 patients with… CONTINUE READING