Hypocretin /orexin preferentially activates caudomedial ventral tegmental area dopamine neurons.


The hypocretin/orexin (HCRT) neuropeptide system modulates behavioral state and state-dependent processes via actions on multiple neuromodulatory transmitter systems. Recent studies indicate that HCRT selectively increases dopamine (DA) neurotransmission within the prefrontal cortex (PFC) and the shell subregion of the nucleus accumbens (NAs), but not the… (More)
DOI: 10.1111/j.1460-9568.2008.06453.x


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