Hypocholesterolemia in patients treated with recombinant interleukin-2: appearance of remnant-like lipoproteins.

Abstract

Reversible acute hypocholesterolemia was observed during treatment of metastatic cancer with high-dose intravenous recombinant interleukin-2 (IL-2). Further analysis revealed virtual disappearance of high-density lipoproteins (HDLs) and marked reduction in the concentration of low-density lipoproteins (LDL); the remaining LDL and intermediate-density… (More)

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@article{Wilson1989HypocholesterolemiaIP, title={Hypocholesterolemia in patients treated with recombinant interleukin-2: appearance of remnant-like lipoproteins.}, author={D Erin Wilson and George Birchfield and Jalal Hejazi and Jonathan Ward and Wolfram E Samlowski}, journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology}, year={1989}, volume={7 10}, pages={1573-7} }