Hypoalaninemia: a concomitant of ketotic hypoglycemia.

  title={Hypoalaninemia: a concomitant of ketotic hypoglycemia.},
  author={Anthony S Pagliara and I E Kari and Darryl C. De Vivo and Ralph D. Feigin and David Kipnis},
  journal={The Journal of clinical investigation},
  volume={51 6},
The cause of of ketotic hypoglycemia, the commonest form of hypoglycemia in childhood, is not known. The present study was undertaken to determine whether the primary defect in this condition is a deficiency of gluconeogenic precursor(s) or an abnormality in the hepatic gluconeogenic enzyme system. Plasma glucose, alanine, and insulin and blood beta-hydroxybutyrate (beta-OHB), pyruvate, and lactate levels were determined in eight ketotic hypoglycemic children and seven agematched controls… CONTINUE READING