Hypoadiponectinaemia in diabetes mellitus type 2: molecular mechanisms and clinical significance.

@article{Su2011HypoadiponectinaemiaID,
  title={Hypoadiponectinaemia in diabetes mellitus type 2: molecular mechanisms and clinical significance.},
  author={Hui Su and Wayne Bond Lau and Xin-liang Ma},
  journal={Clinical and experimental pharmacology & physiology},
  year={2011},
  volume={38 12},
  pages={
          897-904
        }
}
1. This review focuses on the regulatory mechanisms of adiponectin (APN) gene expression during physiologic conditions and both the clinical significance and underlying molecular mechanisms of hypoadiponectinaemia during pathologic conditions. 2. Adiponectin is a versatile cardiovascular protective factor. It plays an important role in regulating insulin sensitivity and energy homeostasis, with anti-inflammatory and anti-atherosclerotic properties. 3. Adiponectin gene expression is… CONTINUE READING

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