Hypoactive medial prefrontal cortex functioning in adults reporting childhood emotional maltreatment.

@article{Harmelen2014HypoactiveMP,
  title={Hypoactive medial prefrontal cortex functioning in adults reporting childhood emotional maltreatment.},
  author={Anne-Laura van Harmelen and Marie-Jos{\'e} van Tol and Tim Dalgleish and Nic van der Wee and Dick J. Veltman and Andr{\'e} Aleman and Philip Spinhoven and Brenda W. J. H. Penninx and Bernet M. Elzinga},
  journal={Social cognitive and affective neuroscience},
  year={2014},
  volume={9 12},
  pages={
          2026-33
        }
}
Childhood emotional maltreatment (CEM) has adverse effects on medial prefrontal cortex (mPFC) morphology, a structure that is crucial for cognitive functioning and (emotional) memory and which modulates the limbic system. In addition, CEM has been linked to amygdala hyperactivity during emotional face processing. However, no study has yet investigated the functional neural correlates of neutral and emotional memory in adults reporting CEM. Using functional magnetic resonance imaging, we… CONTINUE READING
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