Hypnotics' association with mortality or cancer: a matched cohort study

  title={Hypnotics' association with mortality or cancer: a matched cohort study},
  author={D. Kripke and R. Langer and L. Kline},
  journal={BMJ Open},
  • D. Kripke, R. Langer, L. Kline
  • Published 2012
  • Medicine
  • BMJ Open
  • Objectives An estimated 6%–10% of US adults took a hypnotic drug for poor sleep in 2010. This study extends previous reports associating hypnotics with excess mortality. Setting A large integrated health system in the USA. Design Longitudinal electronic medical records were extracted for a one-to-two matched cohort survival analysis. Subjects Subjects (mean age 54 years) were 10 529 patients who received hypnotic prescriptions and 23 676 matched controls with no hypnotic prescriptions, followed… CONTINUE READING
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