• Medicine
• Published in BMJ open 2012
• DOI:10.1136/bmjopen-2012-000850

Hypnotics' association with mortality or cancer: a matched cohort study

@inproceedings{Kripke2012HypnoticsAW,
  title={Hypnotics' association with mortality or cancer: a matched cohort study},
  author={Daniel F Kripke and Robert D. Langer and Lawrence E. Kline},
  booktitle={BMJ open},
  year={2012}
}

• Daniel F Kripke, Robert D. Langer, Lawrence E. Kline

OBJECTIVES An estimated 6%-10% of US adults took a hypnotic drug for poor sleep in 2010. This study extends previous reports associating hypnotics with excess mortality. SETTING A large integrated health system in the USA. DESIGN Longitudinal electronic medical records were extracted for a one-to-two matched cohort survival analysis. SUBJECTS Subjects (mean age 54 years) were 10 529 patients who received hypnotic prescriptions and 23 676 matched controls with no hypnotic prescriptions… CONTINUE READING

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