Hyphal Death during Colony Development in Streptomyces antibioticus: Morphological Evidence for the Existence of a Process of Cell Deletion in a Multicellular Prokaryote

@article{Migulez1999HyphalDD,
  title={Hyphal Death during Colony Development in Streptomyces antibioticus:  Morphological Evidence for the Existence of a Process of Cell Deletion in a  Multicellular Prokaryote },
  author={Elisa M. Migu{\'e}lez and Carlos Hardisson and Manuel B. Manzanal},
  journal={The Journal of Cell Biology},
  year={1999},
  volume={145},
  pages={515 - 525}
}
During the life cycle of the streptomycetes, large numbers of hyphae die; the surviving ones undergo cellular differentiation and appear as chains of spores in the mature colony. Here we report that the hyphae of Streptomyces antibioticus die through an orderly process of internal cell dismantling that permits the doomed hyphae to be eliminated with minimum disruption of the colony architecture. Morphological and biochemical approaches revealed progressive disorganization of the nucleoid… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 33 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Differentiation in Actinomycetes

  • D. A. Hodgson
  • Prokaryotic Structure and Function: A New…
  • 1992
Highly Influential
5 Excerpts

Aspects of multicellular differentiation in Streptomyces coelicolor A3(2)

  • K. F. Chater
  • Genetics and Molecular Biology of Industrial…
  • 1989
Highly Influential
4 Excerpts

Determination of nucleic acids in tissues by pentose analysis

  • W. C. Schneider
  • Methods Enzymol. 3:680–684.
  • 1957
Highly Influential
2 Excerpts

Taking a genetic scalpel to the Streptomyces colony

  • K. F. Chater
  • Microbiology. 144:1465–1478.
  • 1998
1 Excerpt

Multicellularity: the rule, not the exception: lessons from Escherichia coli colonies

  • J. A. Shapiro
  • Bacteria as Multicellular Organisms. J.H. Shapiro…
  • 1997
1 Excerpt

Mycobacterial multicellularity

  • L. J. Shimkets, M. Dworkin.
  • Bacteria as Multicellular Organisms. J.H. Shapiro…
  • 1997
1 Excerpt

Similar Papers

Loading similar papers…