Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury

@inproceedings{Silva2010HypervolemiaIA,
  title={Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury},
  author={Pedro L Silva and Fernanda Ferreira Cruz and L{\'i}via C. Fujisaki and Gisele Pena de Oliveira and Cynthia dos Santos Samary and Debora Dos Santos Ornellas and Tatiana Maron-Gutierrez and Nazareth de Novaes Rocha and Regina dos Santos Goldenberg and Cristiane Snb Garcia and Marcelo Marcos Morales and Vera L{\'u}cia Capelozzi and Marcelo Gama de Abreu and Paolo Pelosi and Patricia R M Rocco},
  booktitle={Critical care},
  year={2010}
}
INTRODUCTION Recruitment maneuvers (RMs) seem to be more effective in extrapulmonary acute lung injury (ALI), caused mainly by sepsis, than in pulmonary ALI. Nevertheless, the maintenance of adequate volemic status is particularly challenging in sepsis. Since the interaction between volemic status and RMs is not well established, we investigated the effects of RMs on lung and distal organs in the presence of hypovolemia, normovolemia, and hypervolemia in a model of extrapulmonary lung injury… CONTINUE READING
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