Hyperventilation-induced cerebral hypoxia.

  title={Hyperventilation-induced cerebral hypoxia.},
  author={J A Kennealy and James E. McLennan and Robert G. Loudon and R L Mclaurin},
  journal={The American review of respiratory disease},
  volume={122 3},
Acute respiratory alkalosis decreases cerebral blood flow, increases the affinity of hemoglobin for oxygen, and can result in cerebral hypoxia. This experiment was designed to study this phenomenon in dogs, and to demonstrate the effect of an increased concentration of inspired oxygen. Seven mongrel dogs were anesthetized with pentobarbital and ventilated with a constant volume respirator. A Telfon-coated stainless steel catheter was placed through a craniotomy into the parietal lobe and… CONTINUE READING
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