Hyperuricemia in pediatric malignancies before treatment.

  title={Hyperuricemia in pediatric malignancies before treatment.},
  author={Ayako Nagai and Masaru Kubota and Li Tang and Souichi Adachi and Ikuya Usami and Kousaku Matsubara},
  journal={Nucleosides, nucleotides & nucleic acids},
  volume={30 12},
The objective of this study was to clarify the prevalence and characteristics of hyperuricemia in various pediatric malignancies before the initiation of treatment. We conducted a retrospective analysis of 119 children with various newly diagnosed malignancies between April 2000 and March 2010. On the basis of the reference values previously established in our laboratory, hyperuricemia was defined as uric acid (UA) levels above 2 standard deviations (s.d.) over the mean values at each age… CONTINUE READING