Hyperuricaemia and gout

  title={Hyperuricaemia and gout},
  author={Amy Kopke and Obw Greeff},
  journal={South African Family Practice},
Gout is a painful, inflammatory disease that affects more men than women. The incidence of gout has increased substantially over the past few decades, as evidenced by information from the Rochester project. Some of the risk factors for the development of gout include: increased ethanol intake, high dietary purine consumption, obesity and the use of certain drugs, such as diuretics. Another important risk factor for the development of gout is hyperuricaemia. Hyperuricaemia results from an… 
The clinical study of primary gout and comparative evaluation of Habb-E-Suranjan with allopurinol in its management
It can be concluded that Habb-e-suranjan and Allopurinol both were significantly effective in resolving the symptoms and signs of gouty arthritis and both have significant effect on reducing serum uric acid level.
MicroCOSM: a model of social and structural drivers of HIV and interventions to reduce HIV incidence in high-risk populations in South Africa
An agent-based ABM of HIV in South Africa is presented, developed to characterize the key social drivers of HIVIn South Africa and the groups that are at the highest risk of HIV.


Metabolic diseases: gout.
The increasing prevalence of gout means that dermatologists will see more cutaneous manifestations of gouts, including tophi, draining sinus tracts, panniculitis, and dystrophic calcifications.
PEG-uricase in the management of treatment-resistant gout and hyperuricemia.
This review describes the development of a poly(ethylene glycol) conjugate of recombinant porcine-like uricase with which a substantial and persistent reduction of plasma urate concentrations has been demonstrated in a Phase 2 clinical trial.
[Establishment of therapeutic goal and plan of gout and asymptomatic hyperuricemia].
  • S. Fujimori
  • Medicine
    Nihon rinsho. Japanese journal of clinical medicine
  • 2008
It is difficult to establish lowering goal of serum urate level in patients with asymptomatic hyperuricemia, so advice regarding lifestyle and treatment of associated comorbidity should be preferred to urate lowering therapy.
Management of hyperuricemia and gout in CKD.
  • A. Gaffo, K. Saag
  • Medicine
    American journal of kidney diseases : the official journal of the National Kidney Foundation
  • 2008
A 55-year-old man with history of kidney transplantation years ago because of diabetic nephropathy has severe ophaceous gout. He has been unable to tolerate treatment ith allopurinol because of
Pain management in gout
The epidemiology, inflammatory pathophysiology, pain management techniques (including recent advances), and treatment of the underlying disease itself are addressed.
Gout: can we create an evidence-based systematic approach to diagnosis and management?
The management of gout can be subdivided into four phases: asymptomatic hyperuricaemia, acute attacks, chronic tophaceous gout, management of anti-inflammatory measures and new agents under development that may help with difficult cases.
An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report
A case of gouty wrist pain possibly precipitated by a medication dosage increase as well as medication interactions is presented and awareness of radiographic changes associated with gout is still of importance although these changes are not seen as frequently as they have been in the past.
A literature review of the epidemiology and treatment of acute gout.
Gout is an increasingly prevalent condition worldwide and creates a heavy economic burden and well-designed, long-term, controlled clinical trials evaluating the comparative efficacy and tolerability of treatments for gout are needed.
Purine-rich foods, dairy and protein intake, and the risk of gout in men.
Higher levels of meat and seafood consumption are associated with an increased risk of gout, whereas a higher level of consumption of dairy products is associated with a decreased risk.
Gout and hyperuricaemia.
The remarkable story of gout and hyperuricaemia in the indigenous populations of the Pacific is recounted and the recent identification of the same problem in communities in rural Indonesia is noted.