Hypertrophy changes the muscarinic receptor subtype mediating bladder contraction from M3 toward M2.

@article{Braverman2003HypertrophyCT,
  title={Hypertrophy changes the muscarinic receptor subtype mediating bladder contraction from M3 toward M2.},
  author={Alan S. Braverman and Michael R Ruggieri},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2003},
  volume={285 3},
  pages={R701-8}
}
Major pelvic ganglion electrocautery (MPGE) and spinal cord injury in the rat induce bladder hypertrophy and a change in muscarinic receptor subtypes mediating bladder contraction from predominantly M3 to a combination of M2 and M3. To determine whether this is a result of bladder hypertrophy or denervation, we studied the following groups: sham-operated controls, urinary diversion (DIV), MPGE together with urinary diversion (DIV-DEN), bilateral MPGE (DEN), bladder outlet obstruction (BOO), and… CONTINUE READING