Hypertrophy and atrophy inversely regulate Caveolin-3 expression in myoblasts.

@article{Fanzani2007HypertrophyAA,
  title={Hypertrophy and atrophy inversely regulate Caveolin-3 expression in myoblasts.},
  author={Alessandro Fanzani and Antonio Musar{\`o} and Elena Stoppani and Roberta Giuliani and Francesca Colombo and Augusto Preti and Sergio Marchesini},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={357 1},
  pages={314-8}
}
Caveolin-3 (Cav-3) is a muscle-specific membrane protein crucial for myoblast differentiation, as loss of the protein due to mutations within the gene causes an autosomal dominant form of limb girdle muscular dystrophy 1-c. Here we show that along with p38 activity the PI3-kinase/AKT/mTOR pathway is required for proper Cav-3 up-regulation during muscle… CONTINUE READING