Hypertrophic cardiomyopathy

  title={Hypertrophic cardiomyopathy},
  author={B. Maron and M. Maron},
  journal={The Lancet},
  • B. Maron, M. Maron
  • Published 2013
  • Medicine
  • The Lancet
  • Hypertrophic cardiomyopathy is a common inherited cardiovascular disease present in one in 500 of the general population. It is caused by more than 1400 mutations in 11 or more genes encoding proteins of the cardiac sarcomere. Although hypertrophic cardiomyopathy is the most frequent cause of sudden death in young people (including trained athletes), and can lead to functional disability from heart failure and stroke, the majority of affected individuals probably remain undiagnosed and many do… CONTINUE READING
    172 Citations

    Paper Mentions

    Interventional Clinical Trial
    Hypertrophic Cardiomyopathy (HCM) is the most common hereditary heart disease with high mortality. Heart failure is the most common complication (about 50% incidence) in these… Expand
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