Hypertrophic Cardiomyopathy

  title={Hypertrophic Cardiomyopathy},
  author={Elijah R. Behr and William J. McKenna},
  journal={Current Treatment Options in Cardiovascular Medicine},
  • E. Behr, W. McKenna
  • Published 1999
  • Medicine
  • Current Treatment Options in Cardiovascular Medicine
Opinion statementWhen an individual is diagnosed with hypertrophic cardiomyopathy (HCM), all relatives potentially affected by Mendelian autosomal-dominant inheritance should be evaluated with an electrocardiogram (ECG) and echocardiogram. Genetic testing should be considered in high-risk mutations where there are diagnostic uncertainties. Symptom relief depends on β-blockers as first-line therapy. If the disease is nonobstructive, then calcium channel blockers can be added or used alone. If… 
2 Citations
Early and midterm results of extended septal myectomy: Indian experience
The aim of the study was to assess the impact of ESM on midterm symptom relief, LVOTO, and survival in patients suffering from HOCM in the Indian population.


Diagnostic value of electrocardiography and echocardiography for familial hypertrophic cardiomyopathy in a genotyped adult population.
ECG and echocardiography have similar diagnostic values for FHC in adults, with an excellent specificity and a lower sensitivity, and the association of the two techniques allows a better evaluation of the risk of being genetically affected in families with hypertrophic cardiomyopathy.
Molecular basis of familial cardiomyopathies.
This clinical classification presents major limitations: specific cardiac diseases such as hypertension or ischemic heart disease, as well as general disorders with cardiac involvement, can mimic the clinical presentation of idiopathic cardiomyopathies.
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  • T. Sakamoto
  • Medicine
    Nihon rinsho. Japanese journal of clinical medicine
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A 75-year-old white man without cardiac symptoms was referred to the cardiology clinic with a long history of abnormal electrocardiographic findings, which demonstrated a marked concentric thickening of the LV apex that gradually decreased to normal levels at the base.
Heterogeneous Morphologic Expression of Genetically Transmitted Hypertrophic Cardiomyopathy: Two–dimensional Echocardiographic Analysis
Almost all patterns of distribution of left ventricular hypertrophy may represent expressions of genetically transmitted hypertrophic cardiomyopathy, and the morphologic appearance of the left ventricle is particularly variable and markedly dissimilar in most closely related individuals with the genetically transmitted form of hypertrophic CARDIomyopathy.
Sudden death due to troponin T mutations.
Apical hypertrophic cardiomyopathy: clinical and two-dimensional echocardiographic assessment.
Most of the patients showed morphologic and clinical features that were dissimilar to those found previously in Japanese patients with apical hypertrophy, which was uncommon in the primarily North American patient population with hypertrophic cardiomyopathy.
Sudden death in hypertrophic cardiomyopathy: identification of high risk patients.