Hypertonic saline solution-hetastarch for fluid resuscitation in experimental septic shock.

@article{Armistead1989HypertonicSS,
  title={Hypertonic saline solution-hetastarch for fluid resuscitation in experimental septic shock.},
  author={C W Armistead and Jean-Louis Vincent and Jean Charles Preiser and Daniel De Backer and Thuc Le Minh},
  journal={Anesthesia and analgesia},
  year={1989},
  volume={69 6},
  pages={714-20}
}
Hypertonic colloid solutions have been found efficacious in the resuscitation from hemorrhagic/traumatic shock. The present study investigated the hemodynamic, gasometric, and metabolic effects of hypertonic colloids in endotoxic shock in the dog. Thirty minutes after administration of 3 mg/kg normal body weight of Escherichia coli endotoxin, dogs were randomly assigned to receive 10 mL/kg hydroxyethylstarch (HES) either in 0.9% NaCl (HES, 10 dogs) or in 7.5% NaCl (HT-HES, 10 dogs) in 30 min… CONTINUE READING

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