Hypertonic saline resuscitation of patients with head injury: a prospective, randomized clinical trial.

@article{Shackford1998HypertonicSR,
  title={Hypertonic saline resuscitation of patients with head injury: a prospective, randomized clinical trial.},
  author={Steven R. Shackford and Paul Bourguignon and Steven L Wald and Frederick B. Rogers and Turner M. Osler and D. Clark},
  journal={The Journal of trauma},
  year={1998},
  volume={44 1},
  pages={50-8}
}
BACKGROUND Experimental and clinical work has suggested that hypertonic saline (HTS) would be better than lactated Ringer's solution (LRS) for the resuscitation of patients with head injuries. No clinical study has examined the effect of HTS infusion on intracranial pressure (ICP) and outcome in patients with head injuries. We hypothesized that HTS infusion… CONTINUE READING